| 1 | Lionel Messi
FC Barcelona | FC Barcelona | 34 | 37 |
| 2 | Luis Suárez
FC Barcelona | FC Barcelona | 35 | 29 |
| 3 | Cristiano Ronaldo
Real Madryt | Real Madryt | 29 | 25 |
| 4 | Iago Aspas
Celta Vigo | Celta Vigo | 32 | 19 |
| 5 | Aritz Aduriz
Athletic Bilbao | Athletic Bilbao | 32 | 16 |
| - | Antoine Griezmann
Atletico Madryt | Atletico Madryt | 36 | 16 |
| 7 | Álvaro Morata
Real Madryt | Real Madryt | 26 | 15 |
| 8 | Sandro Ramírez
Málaga CF | Málaga CF | 30 | 14 |
| 9 | Neymar
FC Barcelona | FC Barcelona | 30 | 13 |
| - | Rubén Castro
Real Betis | Real Betis | 35 | 13 |
| - | Gerard Moreno
RCD Espanyol | RCD Espanyol | 37 | 13 |
| 12 | Kevin Gameiro
Atletico Madryt | Atletico Madryt | 31 | 12 |
| - | Willian José
Real Sociedad | Real Sociedad | 28 | 12 |
| - | Florin Andone
RC Deportivo | RC Deportivo | 37 | 12 |
| 15 | Cedric Bakambu
Villarreal CF | Villarreal CF | 26 | 11 |
| - | Wissam Ben Yedder
Sevilla FC | Sevilla FC | 31 | 11 |
| - | Juanmi
Real Sociedad | Real Sociedad | 35 | 11 |
| - | Karim Benzema
Real Madryt | Real Madryt | 29 | 11 |
| - | Sergi Enrich
SD Eibar | SD Eibar | 38 | 11 |
| 20 | Isco
Real Madryt | Real Madryt | 30 | 10 |
| - | Kevin-Prince Boateng
UD Las Palmas | UD Las Palmas | 28 | 10 |
| - | Yannick Carrasco
Atletico Madryt | Atletico Madryt | 35 | 10 |
| - | Pablo Piatti
RCD Espanyol | RCD Espanyol | 30 | 10 |
| - | Sergio León
CA Osasuna | CA Osasuna | 33 | 10 |
| - | Raúl García
Athletic Bilbao | Athletic Bilbao | 36 | 10 |
| - | Pedro León
SD Eibar | SD Eibar | 37 | 10 |
| 27 | Duje Cop
Real Sporting | Real Sporting | 31 | 9 |
| - | Roberto Soriano
Villarreal CF | Villarreal CF | 33 | 9 |
| - | Carlos Vela
Real Sociedad | Real Sociedad | 35 | 9 |
| 30 | James Rodríguez
Real Madryt | Real Madryt | 22 | 8 |
| - | Fernando Torres
Atletico Madryt | Atletico Madryt | 31 | 8 |
| - | Carlos Carmona
Real Sporting | Real Sporting | 25 | 8 |
| - | Alexander Szymanowski
CD Leganés | CD Leganés | 28 | 8 |
| - | Nicola Sansone
Villarreal CF | Villarreal CF | 32 | 8 |
| - | Pablo Sarabia
Sevilla FC | Sevilla FC | 34 | 8 |
| - | Ivan Rakitic
FC Barcelona | FC Barcelona | 32 | 8 |
| - | Xavier Prieto
Real Sociedad | Real Sociedad | 38 | 8 |
| 38 | Gareth Bale
Real Madryt | Real Madryt | 19 | 7 |
| - | Kenan Kodro
CA Osasuna | CA Osasuna | 28 | 7 |
| - | Vicente Iborra
Sevilla FC | Sevilla FC | 31 | 7 |
| - | Adrián González
SD Eibar | SD Eibar | 28 | 7 |
| - | Kike García
SD Eibar | SD Eibar | 24 | 7 |
| - | Franco Vázquez
Sevilla FC | Sevilla FC | 30 | 7 |
| - | Roberto Torres
CA Osasuna | CA Osasuna | 32 | 7 |
| - | Iker Muniain
Athletic Bilbao | Athletic Bilbao | 35 | 7 |
| - | Sergio Ramos
Real Madryt | Real Madryt | 28 | 7 |
| - | Deyverson
Deportivo Alavés | Deportivo Alavés | 32 | 7 |
| - | Jonathan Viera
UD Las Palmas | UD Las Palmas | 31 | 7 |
| 49 | Paco Alcácer
FC Barcelona | FC Barcelona | 20 | 6 |
| - | Rafinha
FC Barcelona | FC Barcelona | 18 | 6 |