| 1 | Humberto Suazo
Chile | Chile | 0 | 10 |
| 2 | Luis Fabiano
Brazylia | Brazylia | 0 | 9 |
| 3 | Joaquín Botero
Boliwia | Boliwia | 0 | 8 |
| 4 | Diego Forlán
Urugwaj | Urugwaj | 0 | 7 |
| - | Marcelo Moreno
Boliwia | Boliwia | 0 | 7 |
| 6 | Giancarlo Maldonado
Wenezuela | Wenezuela | 0 | 6 |
| - | Salvador Cabañas
Paragwaj | Paragwaj | 0 | 6 |
| 8 | Nelson Valdez
Paragwaj | Paragwaj | 0 | 5 |
| - | Sebastián Abreu
Urugwaj | Urugwaj | 0 | 5 |
| - | Kaká
Brazylia | Brazylia | 0 | 5 |
| - | Nilmar
Brazylia | Brazylia | 0 | 5 |
| - | Luis Suárez
Urugwaj | Urugwaj | 0 | 5 |
| 13 | Edison Méndez
Ekwador | Ekwador | 0 | 4 |
| - | Carlos Bueno
Urugwaj | Urugwaj | 0 | 4 |
| - | Sergio Agüero
Argentyna | Argentyna | 0 | 4 |
| - | Matías Fernández
Chile | Chile | 0 | 4 |
| - | Juan Riquelme
Argentyna | Argentyna | 0 | 4 |
| - | Robinho
Brazylia | Brazylia | 0 | 4 |
| - | Lionel Messi
Argentyna | Argentyna | 0 | 4 |
| 20 | Diego Lugano
Urugwaj | Urugwaj | 0 | 3 |
| - | Christian Benítez
Ekwador | Ekwador | 0 | 3 |
| - | Cristián Riveros
Paragwaj | Paragwaj | 0 | 3 |
| - | José Manuel Rey
Wenezuela | Wenezuela | 0 | 3 |
| - | Walter Ayoví
Ekwador | Ekwador | 0 | 3 |
| - | Roque Santa Cruz
Paragwaj | Paragwaj | 0 | 3 |
| - | Alexis Sánchez
Chile | Chile | 0 | 3 |
| - | Johan Fano
Peru | Peru | 0 | 3 |
| - | Miku
Wenezuela | Wenezuela | 0 | 3 |
| - | Juan Arango
Wenezuela | Wenezuela | 0 | 3 |
| - | Jackson Martínez
Kolumbia | Kolumbia | 0 | 3 |
| 31 | Marcelo Salas
Chile | Chile | 0 | 2 |
| - | Iván Kaviedes
Ekwador | Ekwador | 0 | 2 |
| - | Antonio Valencia
Ekwador | Ekwador | 0 | 2 |
| - | Óscar Cardozo
Paragwaj | Paragwaj | 0 | 2 |
| - | Daniel Arismendi
Wenezuela | Wenezuela | 0 | 2 |
| - | Hugo Rodallega
Kolumbia | Kolumbia | 0 | 2 |
| - | Gonzalo Jara
Chile | Chile | 0 | 2 |
| - | Hernán Rengifo
Peru | Peru | 0 | 2 |
| - | Fabián Orellana
Chile | Chile | 0 | 2 |
| - | Ronald Vargas
Wenezuela | Wenezuela | 0 | 2 |
| - | Paulo da Silva
Paragwaj | Paragwaj | 0 | 2 |
| - | Ruben Bustos
Kolumbia | Kolumbia | 0 | 2 |
| - | Gary Medel
Chile | Chile | 0 | 2 |
| - | Christian Noboa
Ekwador | Ekwador | 0 | 2 |
| - | Ronald García
Boliwia | Boliwia | 0 | 2 |
| - | Julio Baptista
Brazylia | Brazylia | 0 | 2 |
| - | Sebastián Eguren
Urugwaj | Urugwaj | 0 | 2 |
| - | Juan Vargas
Peru | Peru | 0 | 2 |
| 49 | Dayro Moreno
Kolumbia | Kolumbia | 0 | 1 |
| - | Marco Estrada
Chile | Chile | 0 | 1 |